{"id":4,"date":"2025-02-20T20:17:28","date_gmt":"2025-02-20T20:17:28","guid":{"rendered":"https:\/\/iins-prod.onlinecreation.pro\/fr\/what-is-it\/"},"modified":"2025-07-23T13:10:31","modified_gmt":"2025-07-23T13:10:31","slug":"what-is-it","status":"publish","type":"page","link":"http:\/\/iins.u-bordeaux.fr\/en\/what-is-it\/","title":{"rendered":"Presentation"},"content":{"rendered":"\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-1 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-embed aligncenter is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Welcome to the Interdisciplinary Institute for Neuroscience, IINS\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/8btHBg3JkUM?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p>The Interdisciplinary Institute for Neuroscience (IINS) is a research center that opened its doors on January 1<sup>st<\/sup>, 2011. Currently, IINS is home to about 180 scientists. The director is <strong><a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/person\/80144-laurent-groc\/\">Laurent Groc<\/a><\/strong>. IINS undergoes<strong> pluridisciplinary research<\/strong> by associating chemists, biologists, biophysicists and neurobiologists. They particularly study synaptic transmission, i.e. the communication between brain cells and the impact of this communication on neuronal networks and behavior. IINS scientists put a strong emphasis on developments of <strong>new investigation technologies combined with use of advanced tools<\/strong>. This allows the forefront research of subcellular nanoscopic protein organization, synapse dynamic and physiology of neuronal systems in normal or pathological behavioral situations. The IINS research methodologies are <strong>imaging<\/strong>,<strong> chemistry<\/strong>,<strong> cellular biology<\/strong> and the <strong>physiology of synapses<\/strong> and <strong>neuronal networks<\/strong>. The laboratory is leader in the field of <strong>neuronal molecules dynamics<\/strong>. Thanks to IINS studies, synaptic function and receptors are being better understood.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\"><strong>Objectives<\/strong><\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>The core mission of IINS is to contribute to the basic <strong>understanding of the central nervous system function<\/strong>. With this endeavor in mind, we set as an associated objective to develop innovative approaches along our scientific projects and disseminate these through technology transfer. We also aim to contribute, whenever possible, to identify new therapeutic targets and develop new therapeutic strategies for neurological and psychiatric disorders. Currently studied pathologies include <strong>Alzheimer&#8217;s and Huntington&#8217;s diseases, epilepsy, intellectual disability and autism spectrum disorders<\/strong>. Altogether, we represent a unique assembly of expertise, from <strong>structural biology<\/strong> (Team <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/101421-structural-biology-and-engineering-of-neuronal-proteins\/\">Elegheert<\/a>) to integrated <strong>physiology and behavior<\/strong> (Teams <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/56873-synapses-and-neural-circuits-in-behaviour\/\">Carta<\/a>, <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/56862-computational-and-systems-neuroscience\/\">Gambino<\/a>, <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/62033-olfaction-and-memory\/\">Roux<\/a>, <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/124338-neural-basis-of-perception\/\">Takahashi<\/a>), through <strong>cell biology<\/strong> and <strong>chemical biology<\/strong> (Teams <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/56854-dynamic-organization-and-function-of-synapses\/\">Choquet<\/a>, <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/56863-spatio-temporal-and-mechanical-control-of-motile-structures\/\">Giannone<\/a>, <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/56864-developmental-brain-physiology-and-pathology\/\">Groc<\/a>, <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/166552-mechanisms-of-adaptive-processes-in-brain-circuits\/\">Letellier<\/a>, <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/119021-membrane-traffic-at-synapses-memtras\/\">Perrais<\/a>), and <strong>imaging <\/strong>(Teams <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/56879-quantitative-imaging-of-the-cell\/\">Sibarita<\/a>, <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/teams\/129574-organ_izing-the-cells\/\">Studer<\/a>), with relatively focused scientific interests around <strong>excitatory neurotransmission in the brain<\/strong>. This unique combination of joint scientific interests with strong diversity of approaches allows for IINS to be a highly integrated and collaborative environment.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"height:90px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"1000\" src=\"http:\/\/iins-prod.onlinecreation.pro\/wp-content\/uploads\/sites\/27\/2025\/07\/friend-elena-baz-badillo-iins-site-web-3.jpg\" alt=\"\" class=\"wp-image-392\" style=\"width:420px\" srcset=\"https:\/\/www.iins.u-bordeaux.fr\/wp-content\/uploads\/sites\/27\/2025\/07\/friend-elena-baz-badillo-iins-site-web-3.jpg 1000w, https:\/\/www.iins.u-bordeaux.fr\/wp-content\/uploads\/sites\/27\/2025\/07\/friend-elena-baz-badillo-iins-site-web-3-300x300.jpg 300w, https:\/\/www.iins.u-bordeaux.fr\/wp-content\/uploads\/sites\/27\/2025\/07\/friend-elena-baz-badillo-iins-site-web-3-150x150.jpg 150w, https:\/\/www.iins.u-bordeaux.fr\/wp-content\/uploads\/sites\/27\/2025\/07\/friend-elena-baz-badillo-iins-site-web-3-768x768.jpg 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure><\/div><\/div>\n<\/div>\n\n\n\n<p>IINS unites researchers with diverse areas of expertise, and creates a highly synergistic environment to promote:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The development of innovative methods and investigation tools, focusing on those based on <strong>molecular <\/strong>and<strong> structural biology<\/strong>, <strong>physiology<\/strong>, <strong>optics<\/strong>, <strong>chemistry<\/strong>, <strong>physics <\/strong>and <strong>computer science<\/strong>.<\/li>\n\n\n\n<li>The application of these tools to push the boundaries of the study of <strong>molecular <\/strong>and <strong>physiological events <\/strong>underlying the<strong> activity of the brain<\/strong>. This includes studying the morpho-dynamic and functional properties of the nervous system to understand the complexity of its molecular assemblies and functions at an integrated level.<\/li>\n<\/ul>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Scientific objectives<\/strong><\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Identify, study and develop tools to control the <strong>biochemical<\/strong>, <strong>structural <\/strong>and <strong>dynamic properties<\/strong> of <strong>molecular complexes involved in synapses, cell contacts or adhesion sites at a nanometric scale<\/strong>.<\/li>\n\n\n\n<li>Understand the basic mechanisms underlying the establishment and function of <strong>synaptic transmission in the nervous system in normal and pathological conditions<\/strong>.<\/li>\n\n\n\n<li>Integrate this knowledge to understand brain adaptive functions at the <strong>network and behavioral level<\/strong>.<\/li>\n\n\n\n<li>Develop new investigation methods (<strong>structural and chemical biology, nano-imaging, in vivo imaging and physiology, bio-sensors<\/strong>).<\/li>\n\n\n\n<li>Render these technological advances available to the community through core facilities and training activities and industrial technology transfer.<\/li>\n\n\n\n<li>Train next generation of scientists.<\/li>\n<\/ul>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Parents institutions<\/strong><\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>The parent institutions of IINS (UMR 5297) are the <a href=\"https:\/\/www.cnrs.fr\/fr\">Centre National de la Recherche Scientifique<\/a> (CNRS) and the <a href=\"https:\/\/www.u-bordeaux.fr\/\">University of Bordeaux<\/a>.<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Collaborations and partnerships<\/strong><\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>IINS is part of the <a href=\"https:\/\/web.archive.org\/web\/20220307084021\/https:\/\/www.bordeaux-neurocampus.fr\/\">Bordeaux Neurocampus<\/a>&nbsp;department of Bordeaux University that is home to around 700 neuroscientists.<\/p>\n\n\n\n<p>IINS teams have developed an extensive network of collaborations with the various centers, thanks in part to the incentive funding proposed by the <strong>Labex BRAIN<\/strong> for transversal projects.<\/p>\n\n\n\n<p>BRAIN (<a href=\"https:\/\/web.archive.org\/web\/20220307084021\/https:\/\/brain.labex.u-bordeaux.fr\/\">Bordeaux Region Aquitaine Initiative for Neuroscience<\/a>) has been an excellence cluster funded for 10 years (21.7 M\u20ac &#8211; 2011-2020) that gathered all teams of Bordeaux Neurocampus around specific projects. It has been directed by Daniel Choquet. BRAIN has put a strong emphasis of <strong>supporting core facilities, supporting transversal scientific projects through competitive calls, supporting training<\/strong> through helping the creation of the&nbsp;<a href=\"https:\/\/web.archive.org\/web\/20220307084021\/http:\/\/www.bordeaux-school-of-neuroscience.eu\/\">Bordeaux School of Neuroscience<\/a>&nbsp;and providing fellowships for PhD extensions.<\/p>\n\n\n\n<p>Bordeaux Neurocampus and BRAIN joined forces to subsidize organization of workshops, symposiums and international meetings. Every year, over five international meetings are organized by the Bordeaux Neuroscience community.<\/p>\n\n\n\n<p>BRAIN ends December 31<sup>st<\/sup>&nbsp;2020, extended to June 2021 due to the COVID-19 crisis. Bordeaux Neurocampus teams applied for a renewal in a large center project BRAIN_2030 headed by <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/person\/79941-daniel-choquet\/v\">Daniel Choquet<\/a>.<\/p>\n\n\n\n<p>In addition, Bordeaux Neurocampus is proud to be home to the&nbsp;<a href=\"https:\/\/web.archive.org\/web\/20220307084021\/http:\/\/www.bordeaux-school-of-neuroscience.eu\/\" target=\"_blank\" rel=\"noreferrer noopener\">Bordeaux School of Neuroscience<\/a>&nbsp;(chaired by <a href=\"https:\/\/iins-prod.onlinecreation.pro\/en\/person\/79947-david-perrais\/\">David Perrais<\/a>), a unique neuroscience training center in Europe providing advanced&nbsp;\u201chands-on\u201d&nbsp;courses open to the international community. It is the host of prestigious <a href=\"http:\/\/cajal-training.org\/\">Cajal Advanced Training Courses<\/a>&nbsp;and a partner of the <a href=\"https:\/\/neurocampus-graduateprogram.u-bordeaux.fr\/\">Bordeaux Neurocampus Graduate Program<\/a>.<br><\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Organization<\/strong><\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/iins-prod.onlinecreation.pro\/wp-content\/uploads\/sites\/27\/2025\/07\/Organigramme-IINS_2025-07-1024x576.jpg\" alt=\"\" class=\"wp-image-408\" srcset=\"https:\/\/www.iins.u-bordeaux.fr\/wp-content\/uploads\/sites\/27\/2025\/07\/Organigramme-IINS_2025-07-1024x576.jpg 1024w, https:\/\/www.iins.u-bordeaux.fr\/wp-content\/uploads\/sites\/27\/2025\/07\/Organigramme-IINS_2025-07-300x169.jpg 300w, https:\/\/www.iins.u-bordeaux.fr\/wp-content\/uploads\/sites\/27\/2025\/07\/Organigramme-IINS_2025-07-768x432.jpg 768w, https:\/\/www.iins.u-bordeaux.fr\/wp-content\/uploads\/sites\/27\/2025\/07\/Organigramme-IINS_2025-07.jpg 1280w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>The Interdisciplinary Institute for Neuroscience (IINS) is a research center that opened its doors on January 1st, 2011. Currently, IINS [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/iins.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/pages\/4","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/iins.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/iins.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/iins.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/iins.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/comments?post=4"}],"version-history":[{"count":51,"href":"http:\/\/iins.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/pages\/4\/revisions"}],"predecessor-version":[{"id":411,"href":"http:\/\/iins.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/pages\/4\/revisions\/411"}],"wp:attachment":[{"href":"http:\/\/iins.u-bordeaux.fr\/en\/wp-json\/wp\/v2\/media?parent=4"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}