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Bank of Images

Image

  • © U.V. Nägerl team, Jan Tønnesen
  • STED image of a fluorescently labeled neuron in a living brain slice, revealing its complex anatomical architecture of axons, dendrites and synapses
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  • © Choquet team & BIC, Angela Getz & Mathieu Ducros
  • Lattice Light Sheet image of a mouse hippocampal neuron expressing a tagged glutamate receptor (pink) concentrated at synaptic spines. Green is a GFP cell fill.
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  • © Choquet team, Benjamin Compans
  • Image of a cultured hippocampal neuron overlayed with the individual trajectories of glutamate receptors followed by single molecule tracking
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  • © Yves Deris
  • Centre Broca Nouvelle Aquitaine, home to the Interdisciplinary Institute for Neuroscience
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  • © Mulle team, Thomas Jorda & Gaël Barthet
  • Human brain hippocampus slice. The hippocampus is the most vulnerable part of Alzheimer's disease. Complexin 1 protein is marked in green. The synaptogyrine protein 1 is marked in red. These are two presynaptic proteins whose expression is decreased in AD
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  • © Perrais team & BIC, May Bakr
  • "The Paint Pipette" Single-cell electroporation of ~30 pyramidal neurons with the fluorescent protein mScarlet revealing the laminar organization of the entire CA1 region of the hippocampus.
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  • © IINS - Quantitative Imaging of the Cell, Rémi Galland
  • Single molecule localization based super-resolution picture of the microtubule cytoskeleton within a cell spread onto a coverslip (left corner: diffraction limited image – right: depth color coded super-resolved image). Such imaging methods allow for the acquisition of image with resolution down to 10 nm radially and 40 nm axially.
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  • © IINS - Quantitative Imaging of the Cell, Tom Delaire
  • 3D picture of a cyst formed by stem cells grown within an alginate capsule and imaged with the soSPIM technology developed within the team Quantitative Imaging of the Cell. The color code for the imaging depth.
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  • © IINS - Quantitative Imaging of the Cell, Hisham Forrière
  • Single molecule localization based super-resolution picture of the whole nucleus of a suspended cell acquired thanks to the soSPIM technology developed within the team Quantitative Imaging of the Cell. The color code for the single molecule depth.
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  • © Scilight/Nägerl Team
  • SUSHI image of a hippocampal brain slice with a labeled neuron, which was artistically rendered.
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  • © Perrais team & BIC, Silvia Sposini
  • Maximum intensity projection of a fluorescently labelled mouse neuron in culture imaged by confocal microscopy, depicting the expression of neuromodulator receptors. This image also describes the concept of arborization, such as the ability of neurons to branch out in a tree-like manner, with synaptic spines resembling leaves and dendrites looking like branches.
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  • © Andrea Toledo (Teams Choquet and Thoumine)
  • Hippocampal neuronal in culture expressing Nlg1 (gold) and a postsynaptic marker (white)- dSTORM microscopy (top). The same image was treated with glare edges filter (bottom).
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  • © Piette Nathalie - Organ-izing the cells
  • DIV14 Rat Primary Hippocampal Neurons on micropatterned dots of adhesion proteins
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  • © Julie Angibaud and Anne Beghin, Sibarita, Nagerl teams & BIC
  • Confocal image of neurospheres from rat hippocampal cells immunostained for neuronal dendrites (MAP2, green), astrocytes (GFAP, red), cell membranes (Lamin, white) and nuclei (DAPI, blue).
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  • © Joana Ferreira, Groc team
  • Pictured is a reconstructed image of single-molecule super-resolution microscopy (dSTORM) of the subunit GluN2B of NMDA receptors, using the SR-Tesseler software.
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  • © Sarah Rahmati, Organ-izing the Cells and BIC
  • Confocal images of Cortical Spheroids in hydrogel-based microwells immunolabled with Nestin and Lamin
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  • © O. Thoumine. Image generated using FluoSim, a software written by M. Lagardère that allows for the simulation of single molecule dynamics in arbitrary 2D geometries such as this dendritic segment.
  • This image shows the simulated trajectories of membrane receptors which alternate between periods of fast free diffusion in the dentritic shaft (red tracks) and confined motion at post-synaptic densities (blue tracks). FluoSim calculates in real time the positions of hundreds of individual molecules populating the neuronal geometry and provides offline display.
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  • © Ines Gonzalez-Calvo, Choquet team. The complexity of the Purkinje cell dendritic tree observed in cerebellar acute slices during patch-clamp by adding Lucifer Yellow to the internal solution.
  • Purkinje neurons are the main neurons of the cerebellar cortex. They have a very complex and characteristic morphology, their intricate dendrite tree, that is flat, can be observed during whole-cell patch clamp recordings if we add to the internal solution a fluorescent molecule, such as Lucifer Yellow.
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  • © Gaël Barthet, Team Mulle
  • Mossy fibers (axons of granular cells of the hippocampus) marked for Syt7 (blue), Vamp2 (green) and Map2 (red).
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